Efpeglenatide is a drug in which an exendin-4 analog is linked to a human immunoglobulin G4 fragment through a polyethylene glycol (PEG linker), allowing for Fc receptor of neonate (FcRn)-mediated recycling and reduced excretion through the kidneys [50]
Tirzepatide Tirzepatide is a newer option that targets both GLP-1 and GIP receptors
Journal of Neuroscience Research 92 (4): 446-54
WEIGHT EFFECTS OF GLUCAGON-LIKE PEPTIDE-1 Exogenous GLP-1 was soon demonstrated to have other effects of interest in relation to T2DM, most importantly an inhibitory effect on appetite and food intake [9]
Nausea, bloating, constipation, and delayed gastric emptying are common side effects and many of these symptoms overlap with endometriosis-related bowel and pelvic discomfort
Prior weight loss attempts (diet, exercise, or other medications) also need documentation