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85,86 The selective membrane disruption action is similar to its bactericidal action: the cationic AMPs directly interact with the cancer cell membrane through electrostatic attraction to form transient pores and destroy the integrity of the cell membrane and finally cause cell death

on the other hand, tumor metabolic plasticity may lead to therapeutic escape, which calls for the development of more selective combinatorial strategies of inhibitors and blockade of compensatory pathways

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The whole procedure was repeated 200 times with a Monte Carlo cross validation scheme, and the results averaged

387 Pegloticase, a recombinant urate oxidase conjugated to polyethylene glycol (PEG), has been introduced to reduce immunogenicity and extend the half-life of rasburicase

Vitamin C is known for its antioxidant properties, which can help reduce inflammation and protect the skin from oxidative damage, thus soothing eczema-prone skin