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Ruenzi et al., 2005) and the experimental animal models (for review, see Sikiric et al., 2011

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doi: 10.1038/ejcn.2014.46

This bidirectionality BPC-157 can both activate NO production in ischemic/hypoxic tissue and normalize NO dysregulation in inflammatory conditions suggests that the compound does not simply "increase" or "decrease" NO

Preclinical research has shown encouraging impacts on metabolic function and fat reduction without requiring major dietary adjustments