The injectable GLP-1 RAs liraglutide 3 mg once daily and semaglutide 2.4 mg once weekly have both gained a licence for weight loss, alongside lifestyle management, in obese/overweight people without T2D (SmPC, 2023b
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Generalised pruritus and urticaria are uncommon, potentially indicating hypersensitivity reactions
Dehydration is one of the most common culpritsnausea from semaglutide can reduce fluid intake, leaving skin dry and irritated
Similarly, reality television personality Savannah Chrisley has also promoted GLP-1 medications through a wellness brand she owns
In a Phase 2 trial published in 2023, adults with obesity who received retatrutide weekly for 48 weeks lost up to 24.2% of their body weight on the highest dose nearly a quarter of their weight on average