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1 Hemorrhoids may require in-office procedures like rubber band ligation, sclerotherapy, or infrared therapy

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SLH also reports having been paid as a consultant by Procter & Gamble, and having received research funds from Procter & Gamble and Roche

Interactions among various factors, including genetics, the host immune system, microbiome, and environmental factors play an important role in disturbing the intestinal homeostasis, leading to the dysregulated inflammatory response of the GI tract (1, 2, 4-8)

This brief summarizes that literature with the mechanism uncertainty foregrounded