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Images were captured with Leica PL APO CS2 objectives (10/0.40 NA air, 40/1.30 NA oil, and 63/1.40 NA oil)

This could be due to a Zn-induced inhibition of phosphatase activity, leading to Mitogen-activated protein kinase (MAPK) and activator protein-1 (AP-1) activation, resulting in the enhanced IL-8 expression [140]