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Once-daily oral sitagliptin as the first registered representative of DPP-4is, is reported to show reductions in blood glucose and blood pressure, with a neutral effect on body weight and cardiovascular outcomes

It helps the body absorb nutrients better

Individual results and eligibility vary based on clinical evaluation and lab results

Several studies have also provided evidence that mitochondrial function is impaired in diabetes and thus the additional insult of metformin-induced dysfunction would be detrimental to patients with T2DM (145, 146), as was seen with the effects of metformin on old (AD10) C

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Others use them exclusively at night and swear by the difference