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A randomized, double-blinded study found that using e-cigarettes containing nicotine may impact peripheral and central hemodynamics and arterial stiffness, with negative effects on the cardiovascular system at levels comparable to traditional tobacco cigarettes [30]

Most American companies inserted a coupon in the package, which could be exchanged for the actual cards

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But former smokers compared with never smokers were at increased hospitalization risk (RR = 1.20

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