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A century ago, things were considerably different
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For others, that first cigarette of the day can be pretty satisfying
For this purpose, blood was obtained by submandibular vein puncture within 1 hour following the end of nicotine exposure and serum cotinine levels were determined by ELISA (Calbiotech, El Cajon, CA)
Participants currently smoking menthol or non-menthol cigarette brands had similarly high mortality risks compared to never smoking (e.g., death from any cause was about 2 times higher), but quitting substantially reduced the risk of death from both types of cigarettes